TURAMED 10

### TURAMED 10 (chlorodehydromethyltestosterone) Tablets

**HIGHLIGHTS OF PRESCRIBING INFORMATION**
These highlights do not include all the information needed to use TURAMED 10 safely and effectively. See full prescribing information for TURAMED 10.

TURAMED 10 (chlorodehydromethyltestosterone) tablets, for oral use

**INDICATIONS AND USAGE**
TURAMED 10 is an anabolic steroid indicated for investigational use in promoting lean muscle gains, strength, and performance with minimal water retention in performance enhancement settings. Not approved for human therapeutic use in many jurisdictions; consult local regulations (1).

**DOSAGE AND ADMINISTRATION**
– Administer orally.
– Adult males: 20 mg to 40 mg per day.
– Adult females: 5 mg to 10 mg per day (2.1).
– Cycle duration: Typically 6 to 8 weeks.

**DOSAGE FORMS AND STRENGTHS**
Tablets: 10 mg chlorodehydromethyltestosterone (3).

**CONTRAINDICATIONS**
– Known or suspected carcinoma of the prostate or breast in males.
– Known or suspected carcinoma of the breast in females with hypercalcemia.
– Pregnancy (4).
– Hypersensitivity to chlorodehydromethyltestosterone or any component of the formulation (4).

**WARNINGS AND PRECAUTIONS**
– Hepatotoxicity: Monitor liver function tests (5.1).
– Cardiovascular risk: May alter lipid profiles; monitor cholesterol (5.2).
– Androgenic effects: Risk of virilization in females; discontinue if occurs (5.3).
– Suppression of endogenous testosterone: Use post-cycle therapy (5.4).

**ADVERSE REACTIONS**
Common adverse reactions include acne, hair loss, and mild aggression (6).

**DRUG INTERACTIONS**
– Anticoagulants: May enhance effects; monitor prothrombin time (7.1).
– Insulin or oral hypoglycemics: May alter glucose levels; adjust doses (7.2).

**USE IN SPECIFIC POPULATIONS**
– Pregnancy: Contraindicated (8.1).
– Lactation: Not recommended (8.2).
– Pediatric use: Not recommended; risk of premature epiphyseal closure (8.4).
– Geriatric use: Increased risk of prostate issues (8.5).

Revised: 08/2025

**FULL PRESCRIBING INFORMATION**

**1 INDICATIONS AND USAGE**
TURAMED 10 is indicated for investigational use in adults to promote lean muscle mass, enhance strength and endurance, improve recovery, increase fat loss, and boost performance with minimal water retention. It is commonly used in cutting or lean bulking cycles for a defined physique. This product is not approved for any medical condition and should be used under medical supervision.

**2 DOSAGE AND ADMINISTRATION**
**2.1 Recommended Dosage**
Administer orally, preferably with food to reduce gastrointestinal irritation.
– Males: 20 mg to 40 mg daily, divided into 2-3 doses to maintain stable blood levels.
– Females: 5 mg to 10 mg daily, in a single dose to minimize androgenic effects.
– Cycle duration: Typically 6 to 8 weeks to limit hepatotoxicity. Discontinue if adverse effects occur.

**2.2 Preparation and Handling**
Store tablets in original packaging to protect from light and moisture. Do not crush or chew tablets.

**3 DOSAGE FORMS AND STRENGTHS**
Tablets containing 10 mg chlorodehydromethyltestosterone, supplied in bottles of 100 tablets.

**4 CONTRAINDICATIONS**
TURAMED 10 is contraindicated in:
– Patients with known or suspected prostate or breast carcinoma.
– Pregnant women (Category X).
– Patients with hypersensitivity to chlorodehydromethyltestosterone or excipients (e.g., lactose monohydrate).
– Patients with severe hepatic insufficiency due to hepatotoxicity risk.

**5 WARNINGS AND PRECAUTIONS**
**5.1 Hepatotoxicity**
May cause elevated liver enzymes or, rarely, peliosis hepatis. Perform liver function tests before and during therapy; discontinue if jaundice or abnormal tests occur.
**5.2 Cardiovascular Effects**
May alter serum lipid profiles, increasing LDL and decreasing HDL, raising the risk of atherosclerosis. Monitor cholesterol levels periodically during treatment.
**5.3 Androgenic Effects**
Females may experience virilization, including deepening of voice, hirsutism, or clitoromegaly, which may be irreversible. Discontinue immediately if signs of virilization appear.
**5.4 Endocrine Effects**
Suppresses hypothalamic-pituitary-gonadal axis, reducing natural testosterone production. Implement post-cycle therapy to restore hormonal balance.

**6 ADVERSE REACTIONS**
Reported adverse reactions include:
– Dermatologic: Acne, oily skin, male pattern baldness in predisposed individuals.
– Psychiatric: Mild aggression, irritability.
– Endocrine: Libido changes, testicular atrophy, reduced fertility.
– Cardiovascular: Hypertension, altered lipid profiles.
– Hepatic: Elevated AST/ALT, jaundice (rare).

**7 DRUG INTERACTIONS**
**7.1 Anticoagulants**
May increase bleeding risk with warfarin or other anticoagulants; monitor INR or prothrombin time closely.
**7.2 Hypoglycemic Agents**
May alter blood glucose levels, potentially requiring adjustment of insulin or oral antidiabetic doses; monitor closely.
**7.3 Corticosteroids**
Concurrent use may increase risk of edema, particularly in patients with cardiac or renal conditions.

**8 USE IN SPECIFIC POPULATIONS**
**8.1 Pregnancy**
Category X: May cause fetal harm, including virilization of a female fetus. Contraindicated in pregnant women.
**8.2 Lactation**
Excretion in breast milk is unknown; breastfeeding is not recommended due to potential risks to the infant.
**8.4 Pediatric Use**
Not recommended; may cause premature epiphyseal closure, leading to stunted growth.
**8.5 Geriatric Use**
Increased risk of prostatic hypertrophy or carcinoma; monitor prostate health closely during use.

**9 DRUG ABUSE AND DEPENDENCE**
Controlled substance in some jurisdictions. Potential for misuse leading to physical or psychological dependence, particularly with prolonged use or high doses.

**10 OVERDOSAGE**
Symptoms of overdose may include liver toxicity, acne exacerbation, or mild aggression. No specific antidote exists; treat symptomatically and discontinue use immediately.

**11 DESCRIPTION**
TURAMED 10 contains chlorodehydromethyltestosterone, a mild anabolic steroid derived from testosterone. Supplied as 10 mg tablets for oral use. Excipients include lactose monohydrate, microcrystalline cellulose, and magnesium stearate. Half-life: Approximately 16 hours.

**12 CLINICAL PHARMACOLOGY**
**12.1 Mechanism of Action**
Chlorodehydromethyltestosterone binds to androgen receptors, promoting protein synthesis and nitrogen retention with minimal water retention for lean muscle gains.
**12.3 Pharmacokinetics**
Absorbed orally; peak plasma levels in 2-3 hours; half-life approximately 16 hours; metabolized in the liver; excreted primarily in urine.

**13 NONCLINICAL TOXICOLOGY**
Animal studies indicate potential hepatotoxicity and carcinogenicity, including hepatic tumors; no human data available.

**16 HOW SUPPLIED/STORAGE AND HANDLING**
Tablets, 10 mg, in bottles of 100. Store at 20°-25°C (68°-77°F); protect from light and moisture. Keep out of reach of children.

*Manufactured by: Medi Pharma*